Mouse BAFF/CD257 (B-cell Activating Factor) ELISA Kit

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935106861
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name
Mouse BAFF/CD257 (B-cell Activating Factor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0019
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 62.5-4000pg/ml |
Sensitivity | 37.5pg/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q9WU72 |
Alias | Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1 |
Background | Elisa kits for TNFSF13B |
Status | RUO |
TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.
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