Mouse Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) ELISA Kit

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Description
Mouse Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 12.5 pg/ml - 800 pg/ml |
Sensitivity | < 4.9 pg/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q9WU72 |
Gene ID | 24099 |
OMIM | 603969 |
Alias | Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1 |
Background | Elisa kits for TNFSF13B |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.
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