Mouse B-Cell Activating Factor (BAFF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse B-Cell Activating Factor (BAFF) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of B-Cell Activating Factor (BAFF)No significant cross-reactivity or interference between B-Cell Activating Factor (BAFF) and analogues was observed.
B-cell activating factor (BAFF), also called tumor necrosis factor ligand superfamily member 13B (TNFSF13B) and CD257, is a protein encoded by the TNFSF13B gene in humans. BAFF is also known by other names, including B Lymphocyte Stimulator (BLyS),CD257, TNF- and APOL-related leukocyte expressed ligand (TALL-1). The human BAFF protein consists of two glycosylated domains and one transmembrane domain (amino acids 48-68), and it can undergo cleavage into both membrane-bound and soluble peptide fragments. BAFF is primarily expressed in cells within the B cell lineage and serves as a potent activator of B cells. It plays a crucial role in promoting the proliferation and differentiation of B cells, making it a pivotal cytokine in the immune system's function.
El factor activador de células B (BAFF), también llamado miembro 13B de la superfamilia del ligando del factor de necrosis tumoral (TNFSF13B) y CD257, es una proteína codificada por el gen TNFSF13B en humanos. BAFF también se conoce con otros nombres, incluido estimulador de linfocitos B (BLyS), CD257, y TALL-1 (APOL-related leukocyte expressed ligand). La proteína BAFF humana consta de dos dominios glicosilados y un dominio transmembrana (aminoácidos 48-68) y puede sufrir escisión en fragmentos peptídicos solubles y unidos a la membrana. BAFF se expresa principalmente en células del linaje de células B y sirve como un potente activador de las células B. Desempeña un papel crucial en la promoción de la proliferación y diferenciación de las células B, lo que la convierte en una citoquina fundamental en la función del sistema inmunológico.
ELISA Kits
Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)
Mouse
12.5 pg/ml - 800 pg/ml
< 4.9 pg/ml
Sandwich
Quantitative
Colorimetric
Serum,Plasma,Other biological fluids
96 tests
5 × 96 tests
10 × 96 tests
B lymphocyte stimulator,BLyS,BAFF,B-cell-activating factor
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
TNFSF13B
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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