Mouse ATP Binding Cassette Transporter A2 (ABCA2) Protein

Este producto es parte de ABCA2 - ATP Binding Cassette Transporter A2
Mouse ATP Binding Cassette Transporter A2 (ABCA2) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein ABCA2

proveedor

Abbexa

reference

abx650372

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse ABCA2 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

ABCA2 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid metabolism and intracellular cholesterol transport. It is primarily expressed in the brain, liver, and macrophages, where it plays a role in maintaining cellular lipid homeostasis and the transport of sterols and sphingolipids. Structurally, ABCA2 contains two transmembrane domains and two nucleotide-binding domains, which use ATP hydrolysis to drive lipid translocation across intracellular membranes. ABCA2 is implicated in myelin formation and neuronal function, highlighting its importance in the central nervous system. Dysregulation of ABCA2 expression has been associated with neurodegenerative diseases, such as Alzheimer’s disease, and certain cancers, where it may contribute to drug resistance by altering cellular lipid composition.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

ATP Binding Cassette Transporter A2 (ABCA2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 30.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu2201-Cys2434 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ABCA2


dry ice

No


availability

Shipped within 5-7 working days.


alias

MRX,MXR,ABCP,BCRP,BMDP,MXR1,ABC15,BCRP1,CD338


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

anti- ABCA2 antibody

anti- ABCA2 antibody

proveedor

FineTest

reference

FNab00027

Tested Applications

ELISA, WB, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and n...

Precio a consultar

Ver más

ATP Binding Cassette Transporter A2 (ABCA2) Antibody

ATP Binding Cassette Transporter A2 (ABCA2) Antibody

proveedor

Abbexa

reference

abx111159

Tested Applications

ELISA, WB

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Atp-Binding Cassette, Sub-Family A (Abc1), Member 2 Antibody is a Rabbit Polyclonal antibody against Atp-Binding Cassett...

637€ (100 µl)

Ver más

ATP Binding Cassette Transporter A2 (ABCA2) Antibody

ATP Binding Cassette Transporter A2 (ABCA2) Antibody

proveedor

Abbexa

reference

abx130547

Tested Applications

WB, IHC, IF/ICC

reactivity

Mouse

status

RUO

clonality

Polyclonal

ABCA2 Antibody is a Rabbit Polyclonal against ABCA2.

286€ (100 µl)

Ver más