Mouse ATP Binding Cassette TransPorter A13 (ABCA13) Protein
234€ (10 µg)
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935106861
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name
Mouse ATP Binding Cassette TransPorter A13 (ABCA13) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650402
tested applications
WB, SDS-PAGE
Description
Mouse ABCA13 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Transporter A13 (ABCA13) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 56.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met4692-Trp4931 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5SSE9 |
| Alias | ATP-binding cassettE sub-family A (ABC1) member 13 |
| Background | Protein ABCA13 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ABCA13 (ATP-binding cassette subfamily A member 13) is a member of the ATP-binding cassette (ABC) transporter superfamily, a large group of proteins that facilitate the transport of various substrates across cellular membranes. ABCA13, encoded by the ABCA13 gene on chromosome 7p12, is the largest known ABC transporter, with a coding sequence of over 5000 amino acids. Although the precise substrates transported by ABCA13 remain to be fully elucidated, its expression in neural and psychiatric contexts has drawn attention to its potential role in the central nervous system. Emerging studies suggest its involvement in lipid transport, vesicle trafficking, and membrane organization. ABCA13 is predominantly expressed in the brain, particularly in regions associated with neural activity, such as the hippocampus, cortex, and striatum. It has also been detected in other tissues, including the lungs and liver, albeit at lower levels. Dysregulation of ABCA13 has been implicated in neuropsychiatric conditions, such as schizophrenia, bipolar disorder, and depression.
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