ATP Binding Cassette Transporter A13 (ABCA13) Antibody
52€ (10 µg)
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935106861
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name
ATP Binding Cassette Transporter A13 (ABCA13) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014226
tested applications
ELISA, IF/ICC
Description
Rabbit polyclonal antibody against ABCA13 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Transporter A13 (ABCA13) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/100 - 1/500, ELISA: 1/40000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86UQ4 |
| Alias | ATP-binding cassettE sub-family A (ABC1) member 13 |
| Background | Antibody anti-ABCA13 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ABCA13 (ATP-binding cassette subfamily A member 13) is a member of the ATP-binding cassette (ABC) transporter superfamily, a large group of proteins that facilitate the transport of various substrates across cellular membranes. ABCA13, encoded by the ABCA13 gene on chromosome 7p12, is the largest known ABC transporter, with a coding sequence of over 5000 amino acids. Although the precise substrates transported by ABCA13 remain to be fully elucidated, its expression in neural and psychiatric contexts has drawn attention to its potential role in the central nervous system. Emerging studies suggest its involvement in lipid transport, vesicle trafficking, and membrane organization. ABCA13 is predominantly expressed in the brain, particularly in regions associated with neural activity, such as the hippocampus, cortex, and striatum. It has also been detected in other tissues, including the lungs and liver, albeit at lower levels. Dysregulation of ABCA13 has been implicated in neuropsychiatric conditions, such as schizophrenia, bipolar disorder, and depression.
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