Mouse ATP-binding cassette sub-family A member 2 (ABCA2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse ATP-binding cassette sub-family A member 2 (ABCA2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500404
tested applications
ELISA
Description
Mouse ATP-binding cassette sub-family A member 2 (ABCA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-binding cassette sub-family A member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | ATP-binding cassette sub-family A member 2 (ABCA2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P41234 |
| Alias | MRX,MXR,ABCP,BCRP,BMDP,MXR1,ABC15,BCRP1,CD338 |
| Background | Elisa kits for ABCA2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCA2 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid metabolism and intracellular cholesterol transport. It is primarily expressed in the brain, liver, and macrophages, where it plays a role in maintaining cellular lipid homeostasis and the transport of sterols and sphingolipids. Structurally, ABCA2 contains two transmembrane domains and two nucleotide-binding domains, which use ATP hydrolysis to drive lipid translocation across intracellular membranes. ABCA2 is implicated in myelin formation and neuronal function, highlighting its importance in the central nervous system. Dysregulation of ABCA2 expression has been associated with neurodegenerative diseases, such as Alzheimer’s disease, and certain cancers, where it may contribute to drug resistance by altering cellular lipid composition.
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