Mouse ATP-binding cassette sub-family A member 2 (ABCA2) ELISA Kit

Este producto es parte de ABCA2 - ATP Binding Cassette Transporter A2
Mouse ATP-binding cassette sub-family A member 2 (ABCA2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ABCA2

proveedor

Abbexa

reference

abx500404

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse ATP-binding cassette sub-family A member 2 (ABCA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse ATP-binding cassette sub-family A member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ABCA2 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid metabolism and intracellular cholesterol transport. It is primarily expressed in the brain, liver, and macrophages, where it plays a role in maintaining cellular lipid homeostasis and the transport of sterols and sphingolipids. Structurally, ABCA2 contains two transmembrane domains and two nucleotide-binding domains, which use ATP hydrolysis to drive lipid translocation across intracellular membranes. ABCA2 is implicated in myelin formation and neuronal function, highlighting its importance in the central nervous system. Dysregulation of ABCA2 expression has been associated with neurodegenerative diseases, such as Alzheimer’s disease, and certain cancers, where it may contribute to drug resistance by altering cellular lipid composition.

Características del producto

category

ELISA Kits


immunogen target

ATP-binding cassette sub-family A member 2 (ABCA2)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

MRX,MXR,ABCP,BCRP,BMDP,MXR1,ABC15,BCRP1,CD338


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ABCA2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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