Mouse AT1R (angiotensin II receptor type 1) ELISA Kit

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935106861
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name
Mouse AT1R (angiotensin II receptor type 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM1911
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 78.125-5000pg/ml |
Sensitivity | 46.875pg/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q9WVK0 |
Alias | Type-1 angiotensin II receptor , AT1AR, AT1BR, Angiotensin II type-1 receptor, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B |
Background | Elisa kits for AT1R |
Status | RUO |
AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.
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Mouse AT1R (angiotensin II receptor type 1) ELISA Kit
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