Mouse AT1R (angiotensin II receptor type 1) ELISA Kit

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935106861
info@markelab.com
name
Mouse AT1R (angiotensin II receptor type 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM1911
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
78.125-5000pg/ml
Sensitivity
46.875pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9WVK0
Alias
Type-1 angiotensin II receptor , AT1AR, AT1BR, Angiotensin II type-1 receptor, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B
Background
Elisa kits for AT1R
Status
RUO

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

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