Mouse Apolipoprotein C4 (APOC4) Peptide (OVA)

Este producto es parte de APOC4 - Apolipoprotein C4
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494€ (100 µg)

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935106861
info@markelab.com
name
Mouse Apolipoprotein C4 (APOC4) Peptide (OVA)
category
Proteins and Peptides
provider
Abbexa
reference
abx651854
tested applications
WB, SDS-PAGE

Description

Apolipoprotein C4 (APOC4) Peptide (OVA) is a protein from Mouse.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Apolipoprotein C4 (APOC4)
Origin
Mouse
Conjugation
OVA
Observed MW
Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Thr30-Ser45
Expression
Synthetic
Purity
> 90%
Size 1
100 µg
Size 2
200 µg
Size 3
500 µg
Size 4
1 mg
Size 5
5 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q61268
Alias
APOC4, APO-CIV, APOC-IV, apolipoprotein C4,Apolipoprotein C-IV
Background
Protein APOC4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

APOC4 is a lesser-known member of the apolipoprotein C family, encoded within the APOC2-APOC4-APOC3 gene cluster on chromosome 19. It is primarily synthesized in the liver and is associated with VLDL and chylomicrons, suggesting a role in triglyceride metabolism and lipoprotein regulation. Although the exact function of APOC4 is not fully characterized, studies suggest it may modulate the activity of lipoprotein lipase (LPL) and influence triglyceride hydrolysis and clearance. Variants in the APOC4 gene have been linked to elevated plasma triglyceride levels and increased susceptibility to atherosclerosis and metabolic disorders. APOC4 is co-regulated with APOC2 and APOC3, indicating a cooperative role in lipoprotein metabolism and lipid homeostasis. Its physiological significance is under investigation, but its presence in triglyceride-rich lipoproteins highlights its potential contribution to lipid transport and cardiovascular risk. Further research is needed to elucidate the precise biological role of APOC4 and its therapeutic relevance in lipid-related disorders.

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