Mouse Apolipoprotein C4 (APOC4) CLIA Kit

643.5€ (96 tests)
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name
Mouse Apolipoprotein C4 (APOC4) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195176
tested applications
CLIA
Description
Mouse Apolipoprotein C4 (APO-C4) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Apolipoprotein C4 (APO-C4).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | CLIA Kits |
Immunogen Target | Apolipoprotein C4 (APOC4) |
Reactivity | Mouse |
Detection Method | Chemiluminescent |
Assay Data | Quantitative |
Test Range | 62.5 pg/ml - 4000 pg/ml |
Sensitivity | 37.5 pg/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | CLIA |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-12 working days. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
Alias | APOC4, APO-CIV, APOC-IV, apolipoprotein C4,Apolipoprotein C-IV |
Background | CLIA Kits APOC4 |
Status | RUO |
Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
APOC4 is a lesser-known member of the apolipoprotein C family, encoded within the APOC2-APOC4-APOC3 gene cluster on chromosome 19. It is primarily synthesized in the liver and is associated with VLDL and chylomicrons, suggesting a role in triglyceride metabolism and lipoprotein regulation. Although the exact function of APOC4 is not fully characterized, studies suggest it may modulate the activity of lipoprotein lipase (LPL) and influence triglyceride hydrolysis and clearance. Variants in the APOC4 gene have been linked to elevated plasma triglyceride levels and increased susceptibility to atherosclerosis and metabolic disorders. APOC4 is co-regulated with APOC2 and APOC3, indicating a cooperative role in lipoprotein metabolism and lipid homeostasis. Its physiological significance is under investigation, but its presence in triglyceride-rich lipoproteins highlights its potential contribution to lipid transport and cardiovascular risk. Further research is needed to elucidate the precise biological role of APOC4 and its therapeutic relevance in lipid-related disorders.
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