Mouse Apolipoprotein A1 Binding Protein (APOA1BP) Protein

Este producto es parte de APOA1BP - Apolipoprotein A1 Binding Protein
Product Graph
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Apolipoprotein A1 Binding Protein (APOA1BP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167927
tested applications
WB, SDS-PAGE

Description

Apolipoprotein A1 Binding Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Apolipoprotein A1 Binding Protein (APOA1BP)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 28.9 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Leu54-Gln282
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
NAXE AIBP,APOA1BP,YJEFN1
Background
Protein APOA1BP
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Apolipoprotein A1 Binding Protein (APOA1BP), also known as NAXE, is an essential protein implicated in lipid metabolism and cellular detoxification processes. This protein is known for its interaction with apolipoprotein A1 (ApoA1), the primary protein component of high-density lipoprotein (HDL). APOA1BP is involved in HDL assembly and function, playing a crucial role in reverse cholesterol transport, wherein cholesterol is transported from peripheral tissues back to the liver for excretion. Additionally, APOA1BP exhibits enzymatic activity as NAD(P)HX epimerase, facilitating the repair of damaged nicotinamide adenine dinucleotide (NADH) or its phosphate form (NADPH), which are critical cofactors in cellular metabolism. This protective function is vital in maintaining cellular redox homeostasis and preventing metabolic dysfunction. Mutations or deficiencies in APOA1BP/NAXE have been linked to a rare neurological disorder characterized by progressive neurodegeneration and metabolic disturbances. As a result, it is increasingly recognized as a target for therapeutic exploration in metabolic and cardiovascular diseases. Understanding the structural and functional dynamics of APOA1BP continues to advance its potential applications in medical science.

Related Products

EH1180

Human APOA1BP (Apolipoprotein A-I-binding protein) ELISA Kit

Ver Producto
abx104885

Apolipoprotein A1 Binding Protein (APOA1BP) Antibody

Apolipoprotein A1 Binding Protein Antibody is a Rabbit Polyclonal against Apolipoprotein A1 Binding Protein.

Ver Producto
abx104941

Apolipoprotein A1 Binding Protein (APOA1BP) Antibody

Apolipoprotein A1 Binding Protein Antibody is a Rabbit Polyclonal against Apolipoprotein A1 Binding Protein.

Ver Producto