Mouse Apolipoprotein A1 Binding Protein (APOA1BP) Protein
234€ (10 µg)
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935106861
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name
Mouse Apolipoprotein A1 Binding Protein (APOA1BP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167927
tested applications
WB, SDS-PAGE
Description
Mouse Apolipoprotein A1 Binding Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Apolipoprotein A1 Binding Protein (APOA1BP) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Leu54-Gln282 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 28.9 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | NAXE AIBP,APOA1BP,YJEFN1 |
| Background | Protein APOA1BP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Apolipoprotein A1 Binding Protein (APOA1BP), also known as NAXE, is an essential protein implicated in lipid metabolism and cellular detoxification processes. This protein is known for its interaction with apolipoprotein A1 (ApoA1), the primary protein component of high-density lipoprotein (HDL). APOA1BP is involved in HDL assembly and function, playing a crucial role in reverse cholesterol transport, wherein cholesterol is transported from peripheral tissues back to the liver for excretion. Additionally, APOA1BP exhibits enzymatic activity as NAD(P)HX epimerase, facilitating the repair of damaged nicotinamide adenine dinucleotide (NADH) or its phosphate form (NADPH), which are critical cofactors in cellular metabolism. This protective function is vital in maintaining cellular redox homeostasis and preventing metabolic dysfunction. Mutations or deficiencies in APOA1BP/NAXE have been linked to a rare neurological disorder characterized by progressive neurodegeneration and metabolic disturbances. As a result, it is increasingly recognized as a target for therapeutic exploration in metabolic and cardiovascular diseases. Understanding the structural and functional dynamics of APOA1BP continues to advance its potential applications in medical science.
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