Mouse APO-C4(Apolipoprotein C4) ELISA Kit

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name
Mouse APO-C4(Apolipoprotein C4) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0845
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.313-20ng/ml |
Size 1 | 96T |
Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 6 months |
UniProt ID | Q61268 |
Alias | APOC4, APO-CIV, APOC-IV, apolipoprotein C4,Apolipoprotein C-IV |
Background | Elisa Kits APOC4 |
Status | RUO |
APOC4 is a lesser-known member of the apolipoprotein C family, encoded within the APOC2-APOC4-APOC3 gene cluster on chromosome 19. It is primarily synthesized in the liver and is associated with VLDL and chylomicrons, suggesting a role in triglyceride metabolism and lipoprotein regulation. Although the exact function of APOC4 is not fully characterized, studies suggest it may modulate the activity of lipoprotein lipase (LPL) and influence triglyceride hydrolysis and clearance. Variants in the APOC4 gene have been linked to elevated plasma triglyceride levels and increased susceptibility to atherosclerosis and metabolic disorders. APOC4 is co-regulated with APOC2 and APOC3, indicating a cooperative role in lipoprotein metabolism and lipid homeostasis. Its physiological significance is under investigation, but its presence in triglyceride-rich lipoproteins highlights its potential contribution to lipid transport and cardiovascular risk. Further research is needed to elucidate the precise biological role of APOC4 and its therapeutic relevance in lipid-related disorders.
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