Mouse Anoctamin-5 (ANO5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ANO5
proveedor
Abbexareference
abx501828Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Anoctamin-5 (ANO5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin-5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ANO5, also known as TMEM16E, is a calcium-activated phospholipid scramblase with important roles in membrane repair, muscle development, and bone homeostasis. ANO5 is highly expressed in skeletal muscle and cardiac muscle, where it regulates plasma membrane repair mechanisms in response to mechanical stress. Mutations in ANO5 are associated with limb-girdle muscular dystrophy type 2L (LGMD2L) and Miyoshi myopathy type 3, both characterized by progressive muscle weakness and degeneration. ANO5 is also involved in osteoblast differentiation and bone mineralization, highlighting its role in maintaining skeletal integrity. Dysregulation of ANO5 impairs membrane repair and calcium signaling, leading to muscle fiber damage, bone abnormalities, and myopathic diseases.
Características del producto
category
ELISA Kits
immunogen target
Anoctamin-5 (ANO5)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ANO5,GDD1,TMEM16E
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ANO5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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