Mouse Anoctamin-5 (ANO5) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Anoctamin-5 (ANO5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501828
tested applications
ELISA
Description
Mouse Anoctamin-5 (ANO5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin-5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Anoctamin-5 (ANO5) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q75UR0 |
| Gene ID | 233246 |
| Alias | ANO5,GDD1,TMEM16E |
| Background | Elisa kits for ANO5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANO5, also known as TMEM16E, is a calcium-activated phospholipid scramblase with important roles in membrane repair, muscle development, and bone homeostasis. ANO5 is highly expressed in skeletal muscle and cardiac muscle, where it regulates plasma membrane repair mechanisms in response to mechanical stress. Mutations in ANO5 are associated with limb-girdle muscular dystrophy type 2L (LGMD2L) and Miyoshi myopathy type 3, both characterized by progressive muscle weakness and degeneration. ANO5 is also involved in osteoblast differentiation and bone mineralization, highlighting its role in maintaining skeletal integrity. Dysregulation of ANO5 impairs membrane repair and calcium signaling, leading to muscle fiber damage, bone abnormalities, and myopathic diseases.
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Mouse Anoctamin-5 (ANO5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Anoctamin-5 concentrations in tissue homogenates, cell lysates and other biological fluids.
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