Mouse Ankyrin repeat domain-containing protein 2 (ANKRD2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ANKRD2
proveedor
Abbexareference
abx501764Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Ankyrin repeat domain-containing protein 2 (ANKRD2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ankyrin repeat domain-containing protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ANKRD2, also known as Arpp (ankyrin repeat protein with PEST domain), is a member of the muscle ankyrin repeat protein (MARP) family. It is predominantly expressed in skeletal and cardiac muscle, where it localizes to the nucleus and the sarcomere, linking mechanical stress signals to gene expression. ANKRD2 functions as a stress-response protein that regulates transcription in response to mechanical stretch, injury, or oxidative stress. It interacts with key sarcomeric proteins such as titin and myopalladin and participates in processes like muscle differentiation, maintenance, and repair. ANKRD2 is upregulated during muscle damage and various cardiomyopathies, suggesting a role in pathological remodeling. Dysregulation of ANKRD2 has been associated with muscular dystrophies, hypertrophy, and heart failure, where it acts as a molecular sensor that influences cellular survival pathways. Its role in muscle homeostasis highlights its importance in maintaining mechanical stability and cellular adaptation during stress.
Características del producto
category
ELISA Kits
immunogen target
Ankyrin repeat domain-containing protein 2 (ANKRD2)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ANKRD2,ARPP
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ANKRD2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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