Mouse Angiopoietin-Related Protein 7 (ANGPTL7) Protein

Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein ANGPTL7
proveedor
Abbexareference
abx065342Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant ANGPTL7 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
ANGPTL7 is a secreted glycoprotein and a member of the angiopoietin-like (ANGPTL) protein family that regulates extracellular matrix (ECM) remodeling, angiogenesis, and ocular physiology. ANGPTL7 is highly expressed in the cornea and aqueous humor, where it plays a critical role in maintaining intraocular pressure and corneal transparency by modulating ECM composition and fluid outflow. Elevated levels of ANGPTL7 have been linked to primary open-angle glaucoma (POAG), a condition characterized by increased intraocular pressure and optic nerve damage. ANGPTL7 is also involved in tissue homeostasis and fibrosis through its regulation of collagen deposition and matrix degradation. Beyond its ocular functions, ANGPTL7 expression is upregulated under inflammatory conditions, suggesting a role in immune modulation and wound healing. Dysregulation of ANGPTL7 has been observed in certain cancers, where it may contribute to tumor progression by remodeling the tumor microenvironment. Its importance in ocular health and ECM regulation highlights ANGPTL7 as a potential therapeutic target for glaucoma and fibrotic diseases.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Angiopoietin-Related Protein 7 (ANGPTL7)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 38.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln22-Pro337 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ANGPTL7
dry ice
No
availability
Shipped within 5-12 working days.
alias
AngX,CDT6
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Mouse Angptl7 (Angiopoietin-related protein 7) ELISA Kit

proveedor
FineTestreference
EM6148reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- ANGPTL7 antibody

proveedor
FineTestreference
FNab00401Tested Applications
ELISA, WBreactivity
human,mousestatus
RUOclonality
polyclonalPrecio a consultar
Ver másAngiopoietin-Related Protein 7 (ANGPTL7) Antibody

proveedor
Abbexareference
abx014191Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalRabbit polyclonal antibody against ANGPTL7 protein. Immunogen region is C-terminal.
52€ (10 µg)
Ver más