Mouse Angiopoietin-Related Protein 7 (ANGPTL7) Protein

Este producto es parte de ANGPTL - Angiopoietin Like
Mouse Angiopoietin-Related Protein 7 (ANGPTL7) Protein

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935106861

info@markelab.com

Precio

234€ (10 µg)

Protein ANGPTL7

proveedor

Abbexa

reference

abx065342

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant ANGPTL7 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

ANGPTL7 is a secreted glycoprotein and a member of the angiopoietin-like (ANGPTL) protein family that regulates extracellular matrix (ECM) remodeling, angiogenesis, and ocular physiology. ANGPTL7 is highly expressed in the cornea and aqueous humor, where it plays a critical role in maintaining intraocular pressure and corneal transparency by modulating ECM composition and fluid outflow. Elevated levels of ANGPTL7 have been linked to primary open-angle glaucoma (POAG), a condition characterized by increased intraocular pressure and optic nerve damage. ANGPTL7 is also involved in tissue homeostasis and fibrosis through its regulation of collagen deposition and matrix degradation. Beyond its ocular functions, ANGPTL7 expression is upregulated under inflammatory conditions, suggesting a role in immune modulation and wound healing. Dysregulation of ANGPTL7 has been observed in certain cancers, where it may contribute to tumor progression by remodeling the tumor microenvironment. Its importance in ocular health and ECM regulation highlights ANGPTL7 as a potential therapeutic target for glaucoma and fibrotic diseases.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Angiopoietin-Related Protein 7 (ANGPTL7)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 38.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln22-Pro337 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ANGPTL7


dry ice

No


availability

Shipped within 5-12 working days.


alias

AngX,CDT6


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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