Mouse Beta-Amyloid Precursor Protein (APP) CLIA Kit
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935106861
info@markelab.com
Precio
812.5€ (96 tests)
Protein APP
proveedor
Abbexareference
abx492330Tested Applications
CLIAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Beta-Amyloid Precursor Protein (APP) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Mouse Amyloid Precursor Protein (APP) CLIA Kit es un kit CLIA tipo Sandwich para su uso con suero, plasma, homogeneizados de tejido y otros fluidos biológicos.
Background
APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders
Características del producto
category
CLIA Kits
immunogen target
Beta-Amyloid Precursor Protein (APP)
reactivity
Mouse
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.118 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Chemiluminescent
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
APP
dry ice
No
uniprot id
note
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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