Mouse Beta-Amyloid Precursor Protein (APP) CLIA Kit

Este producto es parte de APP - Beta-Amyloid Precursor Protein
Mouse Beta-Amyloid Precursor Protein (APP) CLIA Kit

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935106861

info@markelab.com

Precio

812.5€ (96 tests)

Protein APP

proveedor

Abbexa

reference

abx492330

Tested Applications

CLIA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Beta-Amyloid Precursor Protein (APP) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.


Mouse Amyloid Precursor Protein (APP) CLIA Kit es un kit CLIA tipo Sandwich para su uso con suero, plasma, homogeneizados de tejido y otros fluidos biológicos.


Background

APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders

Características del producto

category

CLIA Kits


immunogen target

Beta-Amyloid Precursor Protein (APP)


reactivity

Mouse


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.118 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Chemiluminescent


sample type

Serum, plasma, tissue homogenates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

APP


dry ice

No


note

El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.


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