Amyloid Precursor Protein Antibody

Product specifications

Primary Antibodies

Amyloid Precursor Protein

Goat

ELISA: 1/25000, WB: 1/5000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

Neat.

200 µl

Liquid

ELISA, WB

Contains 0.1% NaN3.

Shipped within 10-20 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein

Antibody anti-APP

RUO

Concentration: Not determined. - 

Descripción

APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders

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