Mouse AMT (Aminomethyltransferase) ELISA Kit

Este producto es parte de AMT - Aminomethyltransferase mitochondrial
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935106861
info@markelab.com
name
Mouse AMT (Aminomethyltransferase) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0831
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
78.125-5000pg/ml
Sensitivity
46.875pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q8CFA2
Alias
AMT,GCST
Background
Elisa kits for AMT
Status
RUO

AMT or Aminomethyltransferase also known as Glycine N-Methyltransferase (GNMT), plays a role in the metabolism of amino acids, particularly glycine (Glycine cleavage system,GCS). AMT/GNMT is an enzyme found in the mitochondria of cells, particularly in the liver. Its primary function is to catalyze the conversion of glycine to sarcosine (N-methylglycine) in the presence of S-adenosylmethionine (SAM). This reaction is part of the methionine cycle, which is involved in the metabolism of methionine, an essential amino acid. The methionine cycle is important for various metabolic processes, including the synthesis of proteins, DNA, and other molecules. In the methionine cycle, methionine is converted to SAM, which is a universal methyl donor in numerous biological reactions. AMT/GNMT helps regulate the levels of SAM by converting glycine to sarcosine, thereby indirectly affecting methionine metabolism. SAM, produced in the methionine cycle, is a key methyl donor for various methylation reactions which are essential for the regulation of gene expression, metabolism of neurotransmitters, and other critical processes

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