Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) Protein
247€ (10 µg)
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935106861
info@markelab.com
name
Mouse Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167983
tested applications
WB, SDS-PAGE
Description
AIMP1 Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 37.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala2-Lys310 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31230 |
| Alias | p43,HLD3,EMAP2,SCYE1,EMAPII |
| Background | Protein AIMP1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
AIMP1, also known as EMAP II (Endothelial Monocyte-Activating Polypeptide II), is a multifunctional protein that acts as a core component of the multi-aminoacyl-tRNA synthetase complex (MSC), which is essential for protein synthesis. It interacts with various aminoacyl-tRNA synthetases to maintain the stability and functionality of the complex. Beyond its role in translation, AIMP1 has extracellular signaling functions, particularly in modulating immune responses and angiogenesis. When secreted, AIMP1 functions as a cytokine that activates monocytes and endothelial cells, contributing to inflammatory responses and tissue repair. It is also involved in apoptosis, cellular stress responses, and tumor suppression. Dysregulation of AIMP1 is associated with cancer progression, inflammatory diseases, and autoimmune disorders, highlighting its dual roles in intracellular protein synthesis and extracellular signaling.
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