Mouse Alpha Hemoglobin Stabilizing Protein (AHSP) ELISA Kit

Este producto es parte de AHSP - Alpha Hemoglobin Stabilizing Protein
Mouse Alpha Hemoglobin Stabilizing Protein (AHSP) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

643.5€ (96 tests)

Elisa kits for AHSP

proveedor

Abbexa

reference

abx258774

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Alpha Hemoglobin Stabilizing Protein (AHSP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alpha-Hemoglobin Stabilizing Protein (aHSP) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


Background

Alpha Hemoglobin Stabilizing Protein (AHSP) is a molecular chaperone that specifically binds to free alpha-globin subunits during erythropoiesis, stabilizing them and preventing their aggregation or precipitation. This function is critical for maintaining the proper stoichiometry of alpha- and beta-globin chains required for the assembly of functional hemoglobin tetramers. AHSP also protects alpha-globin from oxidative damage by maintaining it in a reduced state. Dysregulation or deficiency of AHSP is associated with hematological disorders such as beta-thalassemia, where excess alpha-globin chains lead to oxidative stress and ineffective erythropoiesis. AHSP is highly expressed in erythroid precursor cells, and its expression is tightly regulated during red blood cell development. Therapeutic approaches that modulate AHSP levels or function are being explored as potential treatments for thalassemias and related hemoglobinopathies.

Características del producto

category

ELISA Kits


immunogen target

Alpha Hemoglobin Stabilizing Protein (AHSP)


reactivity

Mouse


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

< 13.8 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

EDRF,ERAF


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AHSP


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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