Mouse Alpha-1-syntrophin (SNTA1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Alpha-1-syntrophin (SNTA1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx390698
tested applications
ELISA
Description
Mouse Alpha-1-syntrophin (SNTA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse SNTA1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alpha-1-syntrophin (SNTA1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q61234 |
| Alias | SNTA1, LQT12, SNT1, TACIP1, dJ1187J4.5, Syntrophin, alpha 1, syntrophin alpha 1 |
| Background | Elisa kits for SNTA1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Alpha-1-syntrophin (SNTA1) is a modular adaptor protein that interacts with members of the dystrophin-associated glycoprotein complex (DGC), linking the cytoskeleton to membrane-bound signaling proteins. It contains PDZ, PH, and syntrophin-specific domains that facilitate interactions with signaling molecules such as ion channels, nitric oxide synthase (NOS), and kinases, enabling the coordination of signal transduction pathways involved in membrane stability, ion homeostasis, and cellular signaling. SNTA1 is widely expressed in skeletal and cardiac muscle, where it regulates membrane integrity, ion transport, and nitric oxide signaling, critical for muscle contraction and vascular function. Dysregulation of SNTA1 is linked to muscular dystrophies, cardiac arrhythmias, and cancers due to its role in maintaining cytoskeletal organization and signaling balance. Mutations in SNTA1 are associated with long QT syndrome, a condition characterized by cardiac arrhythmias and impaired ion channel regulation. Functional studies highlight its essential role in maintaining cellular signaling, membrane structure, and tissue homeostasis under physiological and pathological conditions.
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