Mouse Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
578.5€ (96 tests)
Elisa kits for ALPL
proveedor
Abbexareference
abx255208Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Alkaline phosphatase, tissue-nonspecific isozyme (ALPL) is an enzyme encoded by the ALPL gene in humans. It is also commonly known as tissue-nonspecific alkaline phosphatase (TNAP). ALPL is a type of alkaline phosphatase found in bone, liver, kidney, and intestine. ALPL plays a crucial role in bone mineralization and is involved in the regulation of phosphate metabolism. It catalyzes the hydrolysis of phosphate esters in an alkaline environment, leading to the release of inorganic phosphate. In bone tissue, ALPL is primarily expressed by osteoblasts, where it helps in the mineralization process by generating inorganic phosphate ions, which are essential for the formation of hydroxyapatite crystals, the main component of bone mineral. Deficiencies or mutations in the ALPL gene can lead to a rare genetic disorder known as hypophosphatasia (HPP). HPP is characterized by defective bone mineralization, resulting in weak and soft bones, skeletal abnormalities, and a range of other symptoms depending on the severity of the condition.
Características del producto
category
ELISA Kits
immunogen target
Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
0.1 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
AP-TNAP,TNS-ALP
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ALPL
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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