Mouse Aldehyde Dehydrogenase 7 Family Member A1 (ALDH7A1) ELISA Kit
728€ (96 tests)
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name
Mouse Aldehyde Dehydrogenase 7 Family Member A1 (ALDH7A1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx576651
tested applications
ELISA
Description
Mouse Aldehyde Dehydrogenase 7 Family Member A1 (ALDH7A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aldehyde Dehydrogenase 7 Family Member A1 (ALDH7A1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aldehyde Dehydrogenase 7 Family Member A1 (ALDH7A1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9DBF1 |
| Gene ID | 110695 |
| Alias | ALDH7A1,ATQ1 |
| Background | Elisa kits for ALDH7A1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ALDH7A1, also known as antiquitin, is a multifunctional enzyme involved in lysine catabolism and aldehyde detoxification. It catalyzes the oxidation of α-aminoadipic semialdehyde to α-aminoadipate, a key step in the lysine degradation pathway. Mutations in ALDH7A1 cause pyridoxine-dependent epilepsy (PDE), a rare inherited disorder characterized by seizures that are responsive to vitamin B6 (pyridoxine) supplementation. ALDH7A1 deficiency leads to the accumulation of toxic intermediates, such as α-aminoadipic semialdehyde, which interfere with neurotransmitter function and neuronal health. ALDH7A1 also plays a role in detoxifying aldehydes generated during lipid peroxidation and oxidative stress, protecting tissues from damage. Its expression in the liver, brain, and kidneys highlights its importance in amino acid metabolism, energy production, and cellular defense against aldehyde toxicity.
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