Mouse Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADH7
proveedor
Abbexareference
abx501121Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alcohol dehydrogenase class 4 mu/sigma chain concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ADH7, also known as retinol dehydrogenase 3, is a member of the class IV alcohol dehydrogenase family and is predominantly expressed in the stomach, esophagus, and liver. Unlike other ADH enzymes, ADH7 shows higher activity towards retinol and long-chain alcohols, playing a critical role in retinoic acid biosynthesis, which is essential for cellular differentiation and growth. Its ability to oxidize ethanol is comparatively limited, but it has significant involvement in detoxifying aromatic and aliphatic alcohols, including those derived from dietary sources. ADH7 is highly relevant in protecting mucosal tissues from alcohol-induced damage, particularly in the upper gastrointestinal tract. Genetic polymorphisms affecting ADH7 activity have been linked to variations in susceptibility to alcohol-related cancers, such as esophageal squamous cell carcinoma, due to differences in acetaldehyde accumulation and oxidative stress. Its role in retinoid metabolism also underscores its significance in regulating developmental and immune processes.
Características del producto
category
ELISA Kits
immunogen target
Alcohol dehydrogenase class 4 mu/sigma chain (ADH7)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ADH4,Gastric alcohol dehydrogenase, Retinol dehydrogenase
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADH7
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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