Mouse Ahcy (Adenosylhomocysteinase) ELISA Kit

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935106861
info@markelab.com
name
Mouse Ahcy (Adenosylhomocysteinase) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0560
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P50247
Alias
SAHH,adoHcyase
Background
Elisa kits for Ahcy
Status
RUO

AHCY, also known as S-adenosylhomocysteine hydrolase, is a critical enzyme in the methionine cycle that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (SAH) into homocysteine and adenosine. This reaction is essential for maintaining cellular methylation reactions, as SAH is a potent inhibitor of methyltransferases. AHCY is ubiquitously expressed and localized in the cytoplasm and nucleus, where it regulates methylation-dependent processes such as DNA and histone modification, gene expression, and cell signaling. Dysregulation of AHCY leads to the accumulation of SAH, disrupting methylation and contributing to diseases such as homocystinuria, cardiovascular disease, and neurodegenerative disorders. Mutations in the AHCY gene can cause autosomal recessive hypermethioninemia. AHCY is also being studied as a potential target in cancer and metabolic disorders due to its pivotal role in methylation homeostasis.

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