Mouse Aggrecan Core Protein (ACAN) Protein

Este producto es parte de ACAN - Aggrecan Core Protein
Mouse Aggrecan Core Protein (ACAN) Protein

Pida mas información

935106861

info@markelab.com

Precio

2301€ (1 mg)

Protein ACAN

proveedor

Abbexa

reference

abx065193

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Aggrecan (AGC) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

The ACAN gene encodes the protein Aggrecan, also known as cartilage-specific proteoglycan core protein or chondroitin sulfate proteoglycan 1. As a member of the lectican family, Aggrecan is a crucial component of the extracellular matrix in cartilaginous tissue, providing resistance to compression. It is a proteoglycan modified with large carbohydrates, with the human form consisting of 2316 amino acids and exhibiting multiple isoforms due to alternative splicing. Aggrecan derives its name from its ability to form large aggregates in cartilage. Mutations in this gene may lead to skeletal dysplasia and spinal degeneration. Various transcript variants encoding different protein isoforms have been identified through alternative splicing.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Aggrecan Core Protein (ACAN)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

1 mg


size 2

5 mg


observerd MW

Molecular Weight: Calculated MW: 12.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly587-Arg684 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ACAN


dry ice

No


availability

Shipped within 1-2 months.


alias

AGC1,AGCAN,CSPG1,CSPGCP,MSK16,Cartilage-specific proteoglycan core protei,CSPC,Chondroitin sulfate proteoglycan core protein 1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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