Mouse ADP Ribosyltransferase 4 (Art4) Protein
1235€ (100 µg)
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935106861
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name
Mouse ADP Ribosyltransferase 4 (Art4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691030
tested applications
SDS-PAGE
Description
Mouse Art4 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse Art4 (NP_080915.1) (Met1-Lys263) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Art4 |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 53.7 kDa Sequence Fragment: Met1-Lys263 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 91% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_080915.1 |
| Alias | ADP-ribosyltransferase C2 and C3 toxin-like 4,Dombrock blood group,DO,DOK1,ARTC4,CD297,DO/ART4,Ecto-ADP-ribosyltransferase 4,Mono(ADP-ribosyl)transferase 4 |
| Background | Protein ART4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADP-ribosyltransferase 4 (ART4), also known as CD297, is an enzyme that belongs to the ART family of ADP-ribosyltransferases. These enzymes mediate the transfer of ADP-ribose from NAD+ (nicotinamide adenine dinucleotide) to specific target proteins, a modification that alters their functions. ADP-ribosylation is a post-translational modification that can impact a variety of cellular processes, such as signaling, immune regulation, and cell differentiation. ART4 is a GPI-anchored ectoenzyme, meaning it is attached to the outer surface of the plasma membrane and targets extracellular proteins. ART4 is particularly known for its association with the Dombrock (Do) blood group system, where variations in ART4 contribute to antigenic diversity on red blood cells. Its functions and expression are implicated in immune cell regulation, and it has been investigated for potential roles in immune and hematologic disorders.
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