Mouse Adenylate kinase 2, mitochondrial (AK2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AK2
proveedor
Abbexareference
abx529304Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Adenylate kinase 2, mitochondrial (AK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Adenylate kinase 2, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AK2 is localized in the mitochondrial intermembrane space and is primarily responsible for ATP production in hematopoietic cells. AK2 catalyzes the same ADP-to-ATP conversion as AK1 but in the mitochondrial compartment, essential for maintaining cellular energy supply. Mutations in AK2 are linked to reticular dysgenesis, a severe immunodeficiency caused by disrupted leukocyte differentiation. AK2 has critical functions in energy homeostasis during apoptosis, as ATP signaling is necessary for programmed cell death. Its role extends to regulating mitochondrial biogenesis and influencing mitochondrial DNA replication. The expression of AK2 is also vital in early embryonic development and immune system maintenance.
Características del producto
category
ELISA Kits
immunogen target
Adenylate kinase 2, mitochondrial (AK2)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ADK2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AK2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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