Mouse Adenylate Cyclase 9 (ADCY9) Protein

Este producto es parte de ADCY - Adenylate Cyclase Type
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234€ (10 µg)

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935106861
info@markelab.com
name
Mouse Adenylate Cyclase 9 (ADCY9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167441
tested applications
WB, SDS-PAGE

Description

Mouse Adenylate Cyclase 9 Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetAdenylate Cyclase 9 (ADCY9)
HostE. coli
OriginMouse
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 54.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr852-Val1065 Tag: N-terminal His tag and GST tag
ExpressionRecombinant
Purity> 95%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP51830
Gene ID11515
AliasAC9,ACIX
BackgroundProtein ADCY9
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADCY9 is expressed in multiple tissues, including the lungs, heart, and immune cells. Unlike calcium-sensitive isoforms, ADCY9 is activated by forskolin and G-protein signaling but is inhibited by calcium. It is crucial for cAMP-mediated signal transduction, particularly in immune response and cardiovascular regulation. ADCY9 has been linked to pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), and cardiovascular disorders. Its modulation of cAMP levels influences cellular responses to hormones, neurotransmitters, and inflammatory signals.

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