Adenylate Cyclase 9 (ADCY9) Antibody
273€ (100 µl)
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Name
Adenylate Cyclase 9 (ADCY9) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx101942
Tested Applications
IHC
Description
Polyclonal Antibody to Adenylate Cyclase 9 (ADCY9).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 9 (ADCY9) Immunogen: ADCY9 (Asp1029-Val1282) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60503 |
| Alias | AC9,ACIX |
| Background | Antibody anti-ADCY9 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY9 is expressed in multiple tissues, including the lungs, heart, and immune cells. Unlike calcium-sensitive isoforms, ADCY9 is activated by forskolin and G-protein signaling but is inhibited by calcium. It is crucial for cAMP-mediated signal transduction, particularly in immune response and cardiovascular regulation. ADCY9 has been linked to pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), and cardiovascular disorders. Its modulation of cAMP levels influences cellular responses to hormones, neurotransmitters, and inflammatory signals.
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