Adenylate Cyclase 9 (ADCY9) Antibody

Este producto es parte de ADCY - Adenylate Cyclase Type
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273€ (100 µl)

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935106861
info@markelab.com
name
Adenylate Cyclase 9 (ADCY9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx101942
tested applications
WB, IHC, IF/ICC

Description

Polyclonal Antibody to Adenylate Cyclase 9 (ADCY9).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAdenylate Cyclase 9 (ADCY9)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
PurificationPurified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1100 µl
Size 2200 µl
Size 31 ml
FormLiquid
Tested ApplicationsWB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityShipped within 5-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDO60503
AliasAC9,ACIX
BackgroundAntibody anti-ADCY9
StatusRUO

Descripción

ADCY9 is expressed in multiple tissues, including the lungs, heart, and immune cells. Unlike calcium-sensitive isoforms, ADCY9 is activated by forskolin and G-protein signaling but is inhibited by calcium. It is crucial for cAMP-mediated signal transduction, particularly in immune response and cardiovascular regulation. ADCY9 has been linked to pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), and cardiovascular disorders. Its modulation of cAMP levels influences cellular responses to hormones, neurotransmitters, and inflammatory signals.

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