Mouse Acyl-coenzyme A thioesterase 6 (ACOT6) ELISA Kit

Este producto es parte de ACOT - Acyl-CoA Thioesterase
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Acyl-coenzyme A thioesterase 6 (ACOT6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500831
tested applications
ELISA

Description

Mouse Acyl-coenzyme A thioesterase 6 (ACOT6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acyl-coenzyme A thioesterase 6 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Acyl-coenzyme A thioesterase 6 (ACOT6)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q32Q92
Gene ID
217700
Alias
C14orf42,c14_5530
Background
Elisa kits for ACOT6
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ACOT6 is a peroxisomal enzyme that hydrolyzes short- and medium-chain acyl-CoA molecules into free fatty acids and CoA, playing a critical role in peroxisomal lipid metabolism and the detoxification of acyl-CoA intermediates. It is expressed in metabolically active tissues such as the liver and kidney, where it participates in the breakdown of branched-chain fatty acids and bile acid intermediates. By regulating acyl-CoA and CoA levels, ACOT6 prevents the accumulation of potentially toxic lipid intermediates while supporting peroxisomal β-oxidation and cellular lipid homeostasis. Dysregulation of ACOT6 has been associated with metabolic disorders, including fatty acid oxidation deficiencies and lipid storage diseases, where impaired lipid processing leads to cellular dysfunction. Its role in maintaining peroxisomal balance underscores its importance in systemic metabolic health and adaptability during periods of metabolic stress.

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