Mouse Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Protein
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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein ACADM
proveedor
Abbexareference
abx650416Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ACADM Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 35.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met131-Asn421 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACADM
dry ice
No
availability
Shipped within 5-7 working days.
alias
ACAD1,MCAD,MCADH
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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