Mouse Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Protein
221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650416
tested applications
WB, SDS-PAGE
Description
Mouse ACADM Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Acyl Coenzyme A Dehydrogenase, C4-To-C12 Straight Chain (ACADM) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met131-Asn421 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P45952 |
| Alias | ACAD1,MCAD,MCADH |
| Background | Protein ACADM |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.
Related Products
Rat Acadm(Medium-chain specific acyl-CoA dehydrogenase, mitochondrial) ELISA Kit
Ver Producto
anti- ACADM antibody
Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein(ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase(ETF dehydrogenase).
Ver Producto