anti- ACADM antibody

Este producto es parte de ACADM - Acyl-CoA Dehydrogenase C-4 To C-12 Straight Chain
anti- ACADM antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ACADM

proveedor

FineTest

reference

FNab00065

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein(ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase(ETF dehydrogenase).


Background

The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

45 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

ACADM


alias

ACAD1,MCAD,MCADH


note

This product is for research use only.


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