Mouse Activin receptor type-1C (ACVR1C) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ACVR1C
proveedor
Abbexareference
abx500958Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Activin receptor type-1C (ACVR1C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Activin receptor type-1C concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACVR1C, also known as ALK7 (Activin Receptor-Like Kinase 7), is a type I receptor in the TGF-β superfamily of signaling proteins. It is primarily activated by ligands such as activins (particularly Activin B) and Nodal. ACVR1C phosphorylates receptor-regulated SMADs, specifically SMAD2/3, which form complexes with SMAD4 to regulate gene transcription. ACVR1C plays critical roles in metabolic regulation, adipogenesis, pancreatic β-cell function, and embryonic development. It is predominantly expressed in tissues like the pancreas, adipose tissue, ovaries, and central nervous system. Dysregulation of ACVR1C has been linked to obesity, insulin resistance, and type 2 diabetes due to its role in fat cell differentiation and energy metabolism. Additionally, its signaling pathway is implicated in tumorigenesis, where it influences cell proliferation and survival.
Características del producto
category
ELISA Kits
immunogen target
Activin receptor type-1C (ACVR1C)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ACTR-IC,Activin receptor-like kinase 7 ,ALK-7
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ACVR1C
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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