Mouse Activin A Receptor Type 2A (ACVR2A) Protein

Este producto es parte de ACVR - Activin A Receptor Type
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234€ (10 µg)

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935106861
info@markelab.com
name
Mouse Activin A Receptor Type 2A (ACVR2A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065137
tested applications
WB, SDS-PAGE

Description

Recombinant Activin A Receptor Type II A (ACVR2A) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Activin A Receptor Type 2A (ACVR2A)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 15.0 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Ala20-Lys95 linked with TALKCTFVAV RAICVMKSPL IFRRWKSHSP LQILLHRSHP DSSTTTTTTE IRLLTKPERK LSWLLPPLSN N

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P27038
Alias
ACVR2,Activin receptor type II,ACTR-IIA
Background
Protein ACVR2A
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ACVR2A is a type II receptor that binds activin ligands and subsequently activates type I receptors like ACVR1B. This receptor is integral to TGF-β/activin signaling, mediating cellular processes like growth, differentiation, and apoptosis. ACVR2A is expressed in various tissues, particularly in the reproductive system. Mutations or loss of ACVR2A function are implicated in cancers such as colorectal carcinoma, where its absence disrupts normal cell cycle control and promotes tumor progression.

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