Mouse 3-Ketoacyl-CoA Thiolase, Mitochondrial (ACAA2) Protein

Pida mas información
935106861
info@markelab.com
Precio
208€ (10 µg)
Protein ACAA2
proveedor
Abbexareference
abx650413Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse ACAA2 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Acetyl Coenzyme A Acyltransferase 2 (ACAA2), also known as mitochondrial 3-ketoacyl-CoA thiolase, is an essential mitochondrial enzyme involved in the beta-oxidation of fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA, which then enters the TCA cycle for ATP production. ACAA2 is highly expressed in energy-demanding tissues such as the liver, heart, and muscle, where it plays a key role in maintaining metabolic flexibility and energy production during fasting or exercise. Mutations or deficiencies in ACAA2 can impair mitochondrial fatty acid oxidation, leading to conditions such as mitochondrial fatty acid oxidation disorders and myopathies. Beyond its metabolic role, ACAA2 activity influences reactive oxygen species (ROS) production and mitochondrial dynamics, linking it to cellular stress responses and metabolic regulation. Ongoing research explores its potential as a therapeutic target for metabolic diseases and mitochondrial dysfunction.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
3-Ketoacyl-CoA Thiolase, Mitochondrial (ACAA2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 36.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg90-Ala397 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACAA2
dry ice
No
availability
Shipped within 5-7 working days.
alias
DSAEC
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
anti- ACAA2 antibody

proveedor
FineTestreference
FNab00059Tested Applications
ELISA, WB, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalAbolishes BNIP3-mediated apoptosis and mitochondrial damage.
Precio a consultar
Ver másRecombinant Human ACAA2

proveedor
FineTestreference
P5185Tested Applications
Western Blot,ELISAstatus
RUOPrecio a consultar
Ver másHuman 3-Ketoacyl-CoA Thiolase, Mitochondrial (ACAA2) Protein

proveedor
Abbexareference
abx073818Tested Applications
SDS-PAGEstatus
RUOAcetyl-COA Acyltransferase 2 is a recombinant enzyme.
234€ (2 µg)
Ver más