Mouse Abcb11 (Bile salt export pump) ELISA Kit

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935106861
info@markelab.com
name
Mouse Abcb11 (Bile salt export pump) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0501
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9QY30
Alias
ABCB11,ABC16,BRIC2,BSEP,PFIC-2,PFIC2,PGY4,SPGP
Background
Elisa kits for Abcb11
Status
RUO

ABCB11, also known as the bile salt export pump (BSEP), is an essential transporter located on the canalicular membrane of hepatocytes. It is responsible for exporting bile salts from the liver into bile, a critical step in the digestion and absorption of dietary fats and the excretion of waste products. ABCB11 is ATP-dependent and plays a vital role in maintaining bile flow and preventing bile salt accumulation, which can damage liver cells. Mutations in the ABCB11 gene are associated with progressive familial intrahepatic cholestasis type 2 (PFIC2), a severe liver disorder characterized by impaired bile salt secretion and liver damage. Dysregulation or inhibition of ABCB11 is also implicated in drug-induced cholestasis and liver injury. Its essential function in bile production and liver health makes it a critical target for understanding and treating cholestatic diseases.

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Mouse Abcb11 (Bile salt export pump) ELISA Kit

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