Mouse A-Kinase Anchor Protein 9 (AKAP9) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse A-Kinase Anchor Protein 9 (AKAP9) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501421
tested applications
ELISA
Description
Mouse A-Kinase Anchor Protein 9 (AKAP9) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse A-Kinase Anchor Protein 9 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | A-Kinase Anchor Protein 9 (AKAP9) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q70FJ1 |
| Gene ID | 100986 |
| Alias | AKAP9, AKAP350, AKAP450 |
| Background | Elisa kits for AKAP9 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AKAP9 is a large scaffold protein localized to centrosomes, Golgi apparatus, and microtubules, where it organizes PKA and other signaling complexes involved in cell cycle regulation, microtubule dynamics, and centrosome cohesion. AKAP9 interacts with proteins such as PKA, phosphatases, and cyclin-dependent kinases (CDKs), regulating mitotic spindle formation, chromosome segregation, and cytokinesis. It is essential for centrosome duplication and microtubule nucleation during interphase and mitosis, ensuring proper cell division. AKAP9 is also involved in Golgi apparatus positioning and trafficking, where it interacts with motor proteins and small GTPases to coordinate intracellular transport. Mutations in AKAP9 are associated with ciliopathies, neurodevelopmental disorders, and cancer due to disrupted centrosome function and mitotic defects. AKAP9 has also been shown to regulate cardiac excitation-contraction coupling by anchoring PKA to ion channels and calcium-handling proteins. Its role in both structural and signaling organization makes it a key regulator of cell division, polarity, and organelle function.
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