Mothers Against Decapentaplegic Homolog 3 (SMAD3) Antibody

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52€ (10 µg)

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935106861
info@markelab.com
name
Mothers Against Decapentaplegic Homolog 3 (SMAD3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx012487
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against Smad3 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:S204, M:S204, R:S204.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Mothers Against Decapentaplegic Homolog 3 (SMAD3)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P84022
Background
Antibody anti-SMAD3
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene &apos;mothers against decapentaplegic&apos; (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

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