MLX Interacting Protein (MLXIP) Antibody

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Description
Mlx Interacting Protein Antibody is a Rabbit Polyclonal antibody against Mlx Interacting Protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MLX Interacting Protein (MLXIP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HAP2 |
| Gene ID | 22877 |
| NCBI Accession | NP_055753.3, NM_014938.5 |
| OMIM | 608090 |
| Background | Antibody anti-MLXIP |
| Status | RUO |
Descripción
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MLXIP antibody
Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).
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MLX Interacting Protein (MLXIP) Antibody
MONDOA forms heterodimers with MLX (MIM 602976) that can bind to and activate transcription from CACGTG E boxes (Billin et al., 2000 [PubMed 11073985]).
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MLX Interacting Protein (MLXIP) Antibody
Mlx Interacting Protein Antibody is a Rabbit Polyclonal antibody against Mlx Interacting Protein.
Ver Producto