MLX Interacting Protein (MLXIP) Antibody

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637€ (100 µl)

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935106861
info@markelab.com
name
MLX Interacting Protein (MLXIP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx113861
tested applications
ELISA, WB, IHC

Description

Mlx Interacting Protein Antibody is a Rabbit Polyclonal antibody against Mlx Interacting Protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
MLX Interacting Protein (MLXIP)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9HAP2
Gene ID
22877
NCBI Accession
NP_055753.3, NM_014938.5
OMIM
608090
Background
Antibody anti-MLXIP
Status
RUO

Descripción

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Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

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