Mitogen Activated Protein Kinase Kinase Kinase 12 (MAP3K12) Antibody
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Description
MAP3K12 Antibody is a Rabbit Polyclonal Antibody against MAP3K12.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mitogen Activated Protein Kinase Kinase Kinase 12 (MAP3K12) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12852 |
| Gene ID | 7786 |
| NCBI Accession | NP_001180440.1 |
| Background | Antibody anti-MAP3K12 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq].
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