Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antibody (HRP)
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Description
MAP2K4 Antibody (HRP) is a Rabbit Polyclonal against MAP2K4 conjugated to HRP.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P45985 |
| Gene ID | 6416 |
| NCBI Accession | NP_001268364.1, NM_001281435.1, NP_003001.1, NM_003010.3 |
| OMIM | 601335 |
| Background | Antibody anti-MAP2K4 |
| Status | RUO |
Descripción
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This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
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