MAP2K4 antibody
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Description
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MAP2K4 (MAP2K4) |
| Host | Rabbit |
| Reactivity | Human, mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P45985 |
| Gene ID | 6416 |
| Alias | Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4, MAPKK 4),JNK-activating kinase 1,MAPK/ERK kinase 4 (MEK 4),SAPK/ERK kinase 1 (SEK1),Stress-activated protein kinase kinase 1 (SAPK kinase 1, SAPKK-1, SAPKK1),c-Jun N-terminal kinase kinase 1 (JNKK),MAP2K4,JNKK1,MEK4,MKK4,PRKMK4,SEK1,SERK1,SKK1 |
| Background | Antibody anti-MAP2K4 |
| Status | RUO |
| Note | Mol. Weight 44 kDa |
Descripción
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This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
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