Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antibody

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286€ (100 µl)

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935106861
info@markelab.com
name
Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104294
tested applications
WB, IHC, IF/ICC

Description

Polyclonal Antibody to Mitogen Activated Protein Kinase Kinase 4 (MAP2K4).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1-5 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Background
Antibody anti-MAP2K4
Status
RUO

Descripción

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This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.

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