Mitogen-Activated Protein Kinase 15 (MAPK15) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Mitogen-Activated Protein Kinase 15 (MAPK15) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx033471
Tested Applications
ELISA, WB, IHC
Description
The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Mitogen-Activated Protein Kinase 15 (MAPK15) Immunogen: KLH-conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 59.8 kDa |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TD08 |
| Background | Antibody anti-MAPK15 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
Mitogen-Activated Protein Kinase 15 (MAPK15) Antibody
Rabbit polyclonal antibody against MAPK15 protein. Immunogen region is Internal.…
Ver producto
Mitogen-Activated Protein Kinase 15 (MAPK15) Antibody
The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal…
Ver producto