Mitochondrial Ribosomal Protein L42 (MRPL42) Antibody
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Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion.Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a protein identified as belonging to both the 28S and the 39S subunits.Alternative splicing results in multiple transcript variants.Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mitochondrial Ribosomal Protein L42 (MRPL42) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y6G3 |
| Gene ID | 28977 |
| OMIM | 611847 |
| Background | Antibody anti-MRPL42 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Mitochondrial Ribosomal Protein L42 (MRPL42) Antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion.Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a protein identified as belonging to both the 28S and the 39S subunits.Alternative splicing results in multiple transcript variants.Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
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Mitochondrial Ribosomal Protein L42 (MRPL42) Antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion.Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a protein identified as belonging to both the 28S and the 39S subunits.Alternative splicing results in multiple transcript variants.Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
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Mitochondrial Ribosomal Protein L42 (MRPL42) Antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion.Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a protein identified as belonging to both the 28S and the 39S subunits.Alternative splicing results in multiple transcript variants.Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
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