Rat Midkine (MDK) Protein
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Description
Midkine Protein is a recombinant cytokine.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Midkine (MDK) |
| Origin | Rat |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE and RP-HPLC) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q9R1S9 |
| Background | Protein MDK |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Midkine (MDK) Antibody
MDK Antibody is a Rabbit Polyclonal antibody against MDK. Midkine, or MDK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MDK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MDK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MDK is a non-glycosylated protein that shows greater than 87% identity between human and mouse. The carboxy-terminus of MDK contains the principle heparin-binding site and the molecule’s neurite-promoting sequences; both the amino- and carboxy-terminal sequences are required for the molecule’s neurotrophic properties. An association between overexpression of MDK and colon adenocarcinoma has been shown in families suffering from familial polyposis. In addition, MDK functions to enhance the activity of plasminogen activator (PA).
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Midkine (MDK) Antibody
Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis (summary by Reynolds et al., 2004 [PubMed 15197188]).
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