Microtubule Associated Protein 2 (MAP2) Antibody

Este producto es parte de MAP2 - microtubule associated protein 2
Microtubule Associated Protein 2 (MAP2) Antibody
357.5€ (100 µg)

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Name
Microtubule Associated Protein 2 (MAP2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx036839
Tested Applications
ELISA, IHC

Description

Rabbit Polyclonal against the MAP2 protein.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Microtubule Associated Protein 2 (MAP2)
Immunogen: Recombinant fragment corresponding to 339-554 AA of human MAP2.
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml.
Recommended Dilution
ELISA: 1/20000 - 1/80000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
MAP-2,MAP2A,MAP2B,MAP2C
Background
Antibody anti-MAP2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Microtubule-associated protein 2 (MAP2) is a protein primarily found in neurons, where it plays a crucial role in stabilizing microtubules, maintaining cell shape, and supporting dendritic development MAP2 is part of a family of microtubule-associated proteins that bind to microtubules and regulate their stability, thereby contributing to the structural integrity of the cytoskeleton In neurons, MAP2 is essential for dendritic growth and synaptic plasticity, as it helps organize microtubules that extend into dendritic spines, the sites of synaptic connections and communication Dysregulation or loss of MAP2 function is associated with neurodegenerative diseases such as Alzheimer's disease and tauopathies, where disrupted microtubule stability leads to impaired neuronal function and neurofibrillary tangles MAP2 also serves as a marker for dendritic structures in neurons and is important for maintaining the organization of the central nervous system during development and in response to injury

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