Microfibrillar-Associated Protein 1 (MFAP1) Antibody

Background

MFAP1 is a crucial structural protein that plays an integral role in the assembly and stability of extracellular matrix (ECM) microfibrils. These microfibrils are critical components of connective tissues and are involved in maintaining tissue elasticity and structural integrity, particularly in organs such as the skin, lungs, and blood vessels. MFAP1 interacts with fibrillin and other ECM proteins to support microfibril formation and functionality. Additionally, MFAP1 has been implicated in cellular signaling pathways that regulate tissue repair and development. Emerging research suggests its potential role in disorders associated with connective tissue abnormalities, such as Marfan syndrome. MFAP1’s expression and regulatory mechanisms remain under investigation, with ongoing studies aiming to better understand its contribution to ECM dynamics and associated pathologies.