Transport and Golgi Organization Protein 1 Homolog / TANGO1 (MIA3) Antibody
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Description
MIA3 Antibody is a Rabbit Polyclonal against MIA3.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Transport and Golgi Organization Protein 1 Homolog / TANGO1 (MIA3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5JRA6 |
| Gene ID | 375056 |
| NCBI Accession | NP_001287796.1, NM_001300867.1, NP_001310992.1, NM_001324063.1, NP_940953.2, NM_198551.3 |
| OMIM | 613455 |
| Background | Antibody anti-MIA3 |
| Status | RUO |
Descripción
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MIA3 antibody
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).
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Transport and Golgi Organization Protein 1 Homolog / TANGO1 (MIA3) Antibody
MIA3 Antibody is a Rabbit Polyclonal against MIA3.
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Transport and Golgi Organization Protein 1 Homolog / TANGO1 (MIA3) Antibody
MIA3 Antibody is a Rabbit Polyclonal against MIA3.
Ver Producto