MHC Class I Polypeptide Related Sequence A/B (MICA/MICB) Antibody (APC / Cyanine 7)
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Description
MHC Class I Polypeptide Related Sequence A/B (MICA/MICB) Antibody (APC / Cyanine 7) is a Mouse Monoclonal against MHC Class I Polypeptide Related Sequence A/B (MICA/MICB).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MHC Class I Polypeptide Related Sequence A/B (MICA/MICB) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | APC / Cyanine 7 |
| Isotype | IgG2a |
| Clone ID | I001 |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| Background | Antibody anti-MICA |
| Status | RUO |
| Note | Concentration: 0.1 mg/ml - |
Descripción
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Human MICA (MHC class I polypeptide-related sequence A) ELISA Kit
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MICA antibody
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
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